Description: Applied Surrogate Endpoint Evaluation Methods with SAS and R by Geert Molenberghs, Theophile Bigirumurame, Marc Buyse, Tomasz Burzykowski, Ziv Shkedy, Leacky Muchene, Nolen Joy Perualila, Ariel Alonso, Wim Van der Elst When a true endpoint is difficult to use because of such factors as long follow-up times or prohibitive cost, it is sometimes possible to use a surrogate endpoint that can be measured in a more convenient or cost-effective way. This book focuses on the use of surrogate endpoint evaluation methods in practice, using SAS and R. FORMAT Hardcover LANGUAGE English CONDITION Brand New Publisher Description An important factor that affects the duration, complexity and cost of a clinical trial is the endpoint used to study the treatments efficacy. When a true endpoint is difficult to use because of such factors as long follow-up times or prohibitive cost, it is sometimes possible to use a surrogate endpoint that can be measured in a more convenient or cost-effective way. This book focuses on the use of surrogate endpoint evaluation methods in practice, using SAS and R. Author Biography Ariel Alonso, Theophile Bigirumurame, Tomasz Burzykowski, Marc Buyse, Geert Molenberghs, Leacky Muchene, Nolen Joy Perualila, Ziv Shkedy, Wim Van der Elst Table of Contents Introductory Material. Introduction. Notation and Example Datasets. The History of Surrogate Endpoint Validation. Contemporary Surrogate Endpoint Evaluation Methods. Multiple-Trial Surrogate Endpoint Evaluation Methods. Two Continuous Outcomes. Two Survival Endpoints. Two Categorical Endpoints. A Categorical and a Continuous Endpoint. A Survival and a Continuous Endpoint. A Survival and a Categorical Endpoint. Two Longitudinal Endpoints. A Longitudinal and a Survival Endpoint. Additional Considerations and Further Topics. Software Details. An Alternative Surrogate Endpoint Evaluation Framework: Causal-Inference. Surrogate Endpoint Evaluation Methods in Small Samples. Construction and Evaluation of Genetic Biomarkers in Early Drug Development Experiments. Additional Considerations. Review "This is a timely text. The number of published studies using surrogate endpoints has increased dramatically since the early work of the 1980s; however, there is a dearth of available texts or software on this topic. Anyone with an interest in surrogate endpoint evaluation would benefit from this text."~Statistics in Medicine Review Quote "This is a timely text. The number of published studies using surrogate endpoints has increased dramatically since the early work of the 1980s; however, there is a dearth of available texts or software on this topic. Anyone with an interest in surrogate endpoint evaluation would benefit from this text." ~Statistics in Medicine Details ISBN1482249367 ISBN-10 1482249367 ISBN-13 9781482249361 Format Hardcover Series Chapman & Hall/CRC Biostatistics Series Place of Publication Oakville Illustrations 20 black & white illustrations Short Title APPLIED SURROGATE ENDPOINT EVA Language English Media Book Author Wim Van der Elst DEWEY 615.50724 Year 2016 Pages 374 Publication Date 2016-12-08 UK Release Date 2016-12-08 Alternative 9780367736552 Audience Postgraduate, Research & Scholarly Publisher Taylor & Francis Inc Imprint Chapman & Hall/CRC Country of Publication United States US Release Date 2016-12-08 We've got this At The Nile, if you're looking for it, we've got it. With fast shipping, low prices, friendly service and well over a million items - you're bound to find what you want, at a price you'll love! TheNile_Item_ID:139831396;
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ISBN-13: 9781482249361
Book Title: Applied Surrogate Endpoint Evaluation Methods with SAS and R
Number of Pages: 374 Pages
Language: English
Publication Name: Applied Surrogate Endpoint Evaluation Methods with Sas and R
Publisher: Apple Academic Press Inc.
Publication Year: 2016
Subject: Medicine
Item Height: 234 mm
Item Weight: 703 g
Type: Textbook
Author: Ariel Alonso, Tomasz Burzykowski, Nolen Joy Perualila, Leacky Muchene, Wim Van der Elst, Geert Molenberghs, Marc Buyse, Ziv Shkedy, Theophile Bigirumurame
Item Width: 156 mm
Format: Hardcover
